Nutritional studies in the preference response to alcohol for Stroke-Prone SHR
نویسندگان
چکیده
منابع مشابه
Genetic subgrouping of stroke-prone SHR and stroke-resistant SHR.
From these results, we can conclude that the developmental pattern of hypertension in the young age is genetically determined and closely related to the incidence of hemorrhage or infarction. These newly selected substrains of SHRSP with higher incidences of cerebral infarction (SP-2) or hemorrhage (SP-1) are regarded as the better models for studying the pathogenesis, treatment, and prevention...
متن کاملPermeability of intracranial extracerebral vessels in stroke-prone SHR.
Permeability of intracranial extracerebral arteries of stroke-prone spontaneously hypertensive rats (SHRSP) was studied using labeling techniques (ferritin and horseradish peroxidase), at the cellular level. In the arterial endothelial cells, the tracer molecules were slowly but constantly transported by the plasmalemmal vesicles to the subendothelial space. This endothelial transportation of t...
متن کاملEffect of acute arterial hypertension in stroke-prone and stroke-resistant SHR.
Acute transient hypertension by norepinephrine was loaded to stroke-resistant (SHRSR), stroke-prone (SHRSP), and normotensive Wistar Kyoto (WK) rats. (SHRSP were most sensitive to norepinephrine in young pre-hypertensive group.) Its effects on cerebral small vessels were studied using Evans Blue to detect the increase of vascular permeability. Severe macroscopic dye-leakages were observed in th...
متن کاملA missense mutation in the Abcg5 gene causes phytosterolemia in SHR, stroke-prone SHR, and WKY rats.
Sitosterolemia is an autosomal recessive disorder caused by mutations in the ABCG5 or ABCG8 half-transporter genes. These mutations disrupt the mechanism that distinguishes between absorbed sterols and is most prominently characterized by hyperabsorption and impaired biliary elimination of dietary plant sterols. Sitosterolemia patients retain 15-20% of dietary plant sterols, whereas normal indi...
متن کاملNaloxone ameliorates the pathophysiologic changes which lead to and attend an acute stroke in stroke-prone/SHR.
Stroke-prone, spontaneously hypertensive rats (SP/SHR) were fed a low protein (8%) fish diet + 1% saline at the time of weaning; some were treated with Naloxone (0.4 mg/100 gms bw/sc/2 X daily/5 days per week). Naloxone-treated animals did not develop high blood pressure or strokes. Sixty-two days after feeding the low protein fish diet, blood pressure levels reached 260-300 mmHg and all of the...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1992
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.33.580